Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL048406-06
Application #
2224472
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1991-09-06
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Albany Medical College
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Albany
State
NY
Country
United States
Zip Code
12208
Bove, K; Neumann, P; Gertzberg, N et al. (2001) Role of ecNOS-derived NO in mediating TNF-induced endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 280:L914-22
Gertzberg, N; Clements, R; Jaspers, I et al. (2000) Tumor necrosis factor-alpha-induced activating protein-1 activity is modulated by nitric oxide-mediated protein kinase G activation. Am J Respir Cell Mol Biol 22:105-15
Ferro, T; Neumann, P; Gertzberg, N et al. (2000) Protein kinase C-alpha mediates endothelial barrier dysfunction induced by TNF-alpha. Am J Physiol Lung Cell Mol Physiol 278:L1107-17
Ferro, T J; Gertzberg, N; Selden, L et al. (1997) Endothelial barrier dysfunction and p42 oxidation induced by TNF-alpha are mediated by nitric oxide. Am J Physiol 272:L979-88
Johnson, A; Ferro, T J (1996) Nitrovasodilator repletion increases TNF-alpha-induced pulmonary edema. J Appl Physiol 80:2151-5
Phelps, D T; Ferro, T J; Higgins, P J et al. (1995) TNF-alpha induces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C. Am J Physiol 269:L551-9
Johnson, A; Phelps, D T; Ferro, T J (1994) Tumor necrosis factor-alpha decreases pulmonary artery endothelial nitrovasodilator via protein kinase C. Am J Physiol 267:L318-25
Serfilippi, G; Ferro, T J; Johnson, A (1994) Activation of protein kinase C mediates altered pulmonary vasoreactivity induced by tumor necrosis factor-alpha. Am J Physiol 267:L282-90
Ferro, T J; Parker, D M; Commins, L M et al. (1993) Tumor necrosis factor-alpha activates pulmonary artery endothelial protein kinase C. Am J Physiol 264:L7-14
Ferro, T J; Hocking, D C; Johnson, A (1993) Tumor necrosis factor-alpha alters pulmonary vasoreactivity via neutrophil-derived oxidants. Am J Physiol 265:L462-71

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