Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL049278-04
Application #
2225419
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1993-01-01
Project End
1997-06-30
Budget Start
1996-02-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Weis Center for Research-Geisinger Clinc
Department
Type
DUNS #
079161360
City
Danville
State
PA
Country
United States
Zip Code
17822

  Publications

McWhinney, C D; Hansen, C; Robishaw, J D (2000) Alpha-1 adrenergic signaling in a cardiac murine atrial myocyte (HL-1) cell line. Mol Cell Biochem 214:111-9
McWhinney, C; Wenham, D; Kanwal, S et al. (2000) Constitutively active mutants of the alpha(1a)- and the alpha(1b)-adrenergic receptor subtypes reveal coupling to different signaling pathways and physiological responses in rat cardiac myocytes. J Biol Chem 275:2087-97
Wenham, D; Rahmatullah, R J; Rahmatullah, M et al. (1997) Differential coupling of alpha1-adrenoreceptor subtypes to phospholipase C and mitogen activated protein kinase in neonatal rat cardiac myocytes. Eur J Pharmacol 339:77-86
Hansen, C A; Schroering, A G; Robishaw, J D (1995) Subunit expression of signal transducing G proteins in cardiac tissue: implications for phospholipase C-beta regulation. J Mol Cell Cardiol 27:471-84
Ray, K; Robishaw, J D (1994) Cloning and sequencing of a rat heart cDNA encoding a G-protein beta subunit related to the human retinal beta 3 subunit. Gene 149:337-40
Robishaw, J D; Hansen, C A (1994) Structure and function of G proteins mediating signal transduction pathways in the heart. Alcohol Clin Exp Res 18:115-20
Hansen, C A; Joseph, S K; Robishaw, J D (1994) Ins 1,4,5-P3 and Ca2+ signaling in quiescent neonatal cardiac myocytes. Biochim Biophys Acta 1224:517-26
Hansen, C A; Schroering, A G; Carey, D J et al. (1994) Localization of a heterotrimeric G protein gamma subunit to focal adhesions and associated stress fibers. J Cell Biol 126:811-9