Jongen-Lavrencic, M; Salesse, S; Delwel, R et al. (2005) BCR/ABL-mediated downregulation of genes implicated in cell adhesion and motility leads to impaired migration toward CCR7 ligands CCL19 and CCL21 in primary BCR/ABL-positive cells. Leukemia 19:373-80
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Melikova, Sofya; Dylla, Scott J; Verfaillie, Catherine M (2004) Phosphatidylinositol-3-kinase activation mediates proline-rich tyrosine kinase 2 phosphorylation and recruitment to beta1-integrins in human CD34+ cells. Exp Hematol 32:1051-6
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Salesse, S; Dylla, S J; Verfaillie, C M (2004) p210BCR/ABL-induced alteration of pre-mRNA splicing in primary human CD34+ hematopoietic progenitor cells. Leukemia 18:727-33
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Dylla, Scott J; Deyle, David R; Theunissen, Koen et al. (2004) Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. Exp Hematol 32:365-74
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Salesse, Stephanie; Verfaillie, Catherine M (2003) BCR/ABL-mediated increased expression of multiple known and novel genes that may contribute to the pathogenesis of chronic myelogenous leukemia. Mol Cancer Ther 2:173-82
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Punzel, Michael; Gupta, Pankaj; Verfaillie, Catherine M (2002) The microenvironment of AFT024 cells maintains primitive human hematopoiesis by counteracting contact mediated inhibition of proliferation. Cell Commun Adhes 9:149-59
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Prosper, F; Verfaillie, C M (2001) Regulation of hematopoiesis through adhesion receptors. J Leukoc Biol 69:307-16
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Zhao, R C; Jiang, Y; Verfaillie, C M (2001) A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector. Blood 97:2406-12
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Jiang, Y; Prosper, F; Verfaillie, C M (2000) Opposing effects of engagement of integrins and stimulation of cytokine receptors on cell cycle progression of normal human hematopoietic progenitors. Blood 95:846-54
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Jiang, Y; Zhao, R C; Verfaillie, C M (2000) Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity. Proc Natl Acad Sci U S A 97:10538-43
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