Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050100-03
Application #
2226206
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1994-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Thiagarajan, P; Le, A; Benedict, C R (1999) Beta(2)-glycoprotein I promotes the binding of anionic phospholipid vesicles by macrophages. Arterioscler Thromb Vasc Biol 19:2807-11
Merten, M; Pakala, R; Thiagarajan, P et al. (1999) Platelet microparticles promote platelet interaction with subendothelial matrix in a glycoprotein IIb/IIIa-dependent mechanism. Circulation 99:2577-82
Arnett, F C; Thiagarajan, P; Ahn, C et al. (1999) Associations of anti-beta2-glycoprotein I autoantibodies with HLA class II alleles in three ethnic groups. Arthritis Rheum 42:268-74
Day, H M; Thiagarajan, P; Ahn, C et al. (1998) Autoantibodies to beta2-glycoprotein I in systemic lupus erythematosus and primary antiphospholipid antibody syndrome: clinical correlations in comparison with other antiphospholipid antibody tests. J Rheumatol 25:667-74
Thiagarajan, P; Shapiro, S S (1998) Lupus anticoagulants and antiphospholipid antibodies. Hematol Oncol Clin North Am 12:1167-92, v
Pereira, B; Benedict, C R; Le, A et al. (1998) Cardiolipin binding a light chain from lupus-prone mice. Biochemistry 37:1430-7
Thiagarajan, P; Le, A; Shapiro, S S (1997) Characterization of beta2-glycoprotein I-dependent and -independent ""antiphospholipid"" antibodies from lupus-prone NZW/BXSB F1 hybrid male mice. Am J Hematol 56:86-92
Thiagarajan, P; Benedict, C R (1997) Inhibition of arterial thrombosis by recombinant annexin V in a rabbit carotid artery injury model. Circulation 96:2339-47
Bauer, T L; Arepally, G; Konkle, B A et al. (1997) Prevalence of heparin-associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery. Circulation 95:1242-6
Thiagarajan, P; Le, A; Snuggs, M B et al. (1996) The role of carboxy-terminal glycosaminoglycan-binding domain of vitronectin in cytoskeletal organization and migration of endothelial cells. Cell Adhes Commun 4:317-25

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