Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL050411-01A1S1
Application #
837975
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1994-04-05
Project End
1999-03-31
Budget Start
1994-04-05
Budget End
1995-03-31
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Dick, Ivy E; Limpitikul, Worawan B; Niu, Jacqueline et al. (2016) A rendezvous with the queen of ion channels: Three decades of ion channel research by David T Yue and his Calcium Signals Laboratory. Channels (Austin) 10:20-32
Gabelli, Sandra B; Yoder, Jesse B; Tomaselli, Gordon F et al. (2016) Calmodulin and Ca(2+) control of voltage gated Na(+) channels. Channels (Austin) 10:45-54
Kwon, Chulan; Tomaselli, Gordon F (2015) Coins of the realm in atrioventricular junction development. Circ Res 116:386-8
Tomaselli, Gordon F (2015) Introduction to a compendium on sudden cardiac death: epidemiology, mechanisms, and management. Circ Res 116:1883-6
Aiba, Takeshi; Farinelli, Federica; Kostecki, Geran et al. (2014) A mutation causing Brugada syndrome identifies a mechanism for altered autonomic and oxidant regulation of cardiac sodium currents. Circ Cardiovasc Genet 7:249-56
Gabelli, Sandra B; Boto, Agedi; Kuhns, Victoria Halperin et al. (2014) Regulation of the NaV1.5 cytoplasmic domain by calmodulin. Nat Commun 5:5126
Aiba, Takeshi; Barth, Andreas S; Hesketh, Geoffrey G et al. (2013) Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure. Circ Arrhythm Electrophysiol 6:546-54
Biswas, Subrata; DiSilvestre, Deborah A; Dong, Peihong et al. (2013) Mechanisms of a human skeletal myotonia produced by mutation in the C-terminus of NaV1.4: is Ca2+ regulation defective? PLoS One 8:e81063
Das, Saumya; Aiba, Takeshi; Rosenberg, Michael et al. (2012) Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling. Circulation 126:2208-19
Aiba, Takeshi; Hesketh, Geoffrey G; Liu, Ting et al. (2010) Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes. Cardiovasc Res 85:454-63

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