Coronary Endothelial Vasoregulation Function

Ku, David D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL050483-03
• Application #: 2226692
• Study Section: Cardiovascular and Renal Study Section (CVB)
• Project Start: 1994-04-01
• Project End: 1998-05-31
• Budget Start: 1996-06-01
• Budget End: 1997-05-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Alabama Birmingham
• Department: Pharmacology
• Type: Schools of Dentistry
• DUNS #: 004514360
• City: Birmingham
• State: AL
• Country: United States
• Zip Code: 35294

Publications

Ku, David D; Abdel-Razek, Tarek T; Dai, Jun et al. (2002) Garlic and its active metabolite allicin produce endothelium- and nitric oxide-dependent relaxation in rat pulmonary arteries. Clin Exp Pharmacol Physiol 29:84-91

Kim-Park, S; Ku, D D (2000) Garlic elicits a nitric oxide-dependent relaxation and inhibits hypoxic pulmonary vasoconstriction in rats. Clin Exp Pharmacol Physiol 27:780-6

Ku, D D; Dai, J (1997) Expression of thrombin receptors in human atherosclerotic coronary arteries leads to an exaggerated vasoconstrictory response in vitro. J Cardiovasc Pharmacol 30:649-57

Fallon, M B; Abrams, G A; Luo, B et al. (1997) The role of endothelial nitric oxide synthase in the pathogenesis of a rat model of hepatopulmonary syndrome. Gastroenterology 113:606-14

Ku, D D; Guo, L; Dai, J et al. (1996) Coronary vascular and endothelial reactivity changes in transgenic mice overexpressing atrial natriuretic factor. Am J Physiol 271:H2368-76