Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050488-04
Application #
2226704
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1993-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Raatikainen, M J; Trankina, M F; Morey, T E et al. (1998) Effects of volatile anesthetics on atrial and AV nodal electrophysiological properties in guinea pig isolated perfused heart. Anesthesiology 89:434-42
Kollias-Baker, C A; Ruble, J; Jacobson, M et al. (1997) Agonist-independent effect of an allosteric enhancer of the A1 adenosine receptor in CHO cells stably expressing the recombinant human A1 receptor. J Pharmacol Exp Ther 281:761-8
Napolitano, C A; Raatikainen, M J; Martens, J R et al. (1996) Effects of intravenous anesthetics on atrial wavelength and atrioventricular nodal conduction in guinea pig heart. Potential antidysrhythmic properties and clinical implications. Anesthesiology 85:393-402
Wang, D; Shryock, J C; Belardinelli, L (1996) Cellular basis for the negative dromotropic effect of adenosine on rabbit single atrioventricular nodal cells. Circ Res 78:697-706
Dennis, D M; Raatikainen, M J; Martens, J R et al. (1996) Modulation of atrioventricular nodal function by metabolic and allosteric regulators of endogenous adenosine in guinea pig heart. Circulation 94:2551-9
Belardinelli, L; Shryock, J C; Song, Y et al. (1995) Ionic basis of the electrophysiological actions of adenosine on cardiomyocytes. FASEB J 9:359-65
Kollias-Baker, C; Xu, J; Pelleg, A et al. (1994) Novel approach for enhancing atrioventricular nodal conduction delay mediated by endogenous adenosine. Circ Res 75:972-80
Kollias-Baker, C; Ruble, J; Dennis, D et al. (1994) Allosteric enhancer PD 81,723 acts by novel mechanism to potentiate cardiac actions of adenosine. Circ Res 75:961-71