Blood Flow Effects on Sickle Erythrocytes & Endothelium

Mc Intire, Larry V.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL050601-03
• Application #: 2226849
• Study Section: Surgery and Bioengineering Study Section (SB)
• Project Start: 1994-01-01
• Project End: 1997-12-31
• Budget Start: 1996-03-05
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Rice University
• Department: Engineering (All Types)
• Type: Schools of Engineering
• DUNS #: 050299031
• City: Houston
• State: TX
• Country: United States
• Zip Code: 77005

Publications

Shiu, Yan-Ting; McIntire, Larry V (2003) In vitro studies of erythrocyte-vascular endothelium interactions. Ann Biomed Eng 31:1299-313

Shiu, Yan-Ting; McIntire, Larry V; Udden, Mark M (2002) Sickle erythrocytes increase prostacyclin and endothelin-1 production by cultured human endothelial cells under flow conditions. Eur J Haematol 68:163-9

Shiu, Y T; Udden, M M; McIntire, L V (2000) Perfusion with sickle erythrocytes up-regulates ICAM-1 and VCAM-1 gene expression in cultured human endothelial cells. Blood 95:3232-41

Natarajan, M; Udden, M M; McIntire, L V (1996) Adhesion of sickle red blood cells and damage to interleukin-1 beta stimulated endothelial cells under flow in vitro. Blood 87:4845-52