Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050615-02
Application #
2226868
Study Section
AIDS and Related Research Study Section 5 (ARRE)
Project Start
1994-12-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Internal Medicine/Medicine
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Lawrence, Sarah O; Simpson-Haidaris, Patricia J (2004) Regulated de novo biosynthesis of fibrinogen in extrahepatic epithelial cells in response to inflammation. Thromb Haemost 92:234-43
Duan, Hai Ou; Simpson-Haidaris, Patricia J (2003) Functional analysis of interleukin 6 response elements (IL-6REs) on the human gamma-fibrinogen promoter: binding of hepatic Stat3 correlates negatively with transactivation potential of type II IL-6REs. J Biol Chem 278:41270-81
Rybarczyk, Brian J; Lawrence, Sarah O; Simpson-Haidaris, Patricia J (2003) Matrix-fibrinogen enhances wound closure by increasing both cell proliferation and migration. Blood 102:4035-43
Pereira, Marian; Rybarczyk, Brain J; Odrljin, Tatjana M et al. (2002) The incorporation of fibrinogen into extracellular matrix is dependent on active assembly of a fibronectin matrix. J Cell Sci 115:609-17
Odrljin, T M; Haidaris, C G; Lerner, N B et al. (2001) Integrin alphavbeta3-mediated endocytosis of immobilized fibrinogen by A549 lung alveolar epithelial cells. Am J Respir Cell Mol Biol 24:12-21
Nguyen, M D; Simpson-Haidaris, P J (2000) Cell type-specific regulation of fibrinogen expression in lung epithelial cells by dexamethasone and interleukin-1beta. Am J Respir Cell Mol Biol 22:209-17
Rybarczyk, B J; Simpson-Haidaris, P J (2000) Fibrinogen assembly, secretion, and deposition into extracellular matrix by MCF-7 human breast carcinoma cells. Cancer Res 60:2033-9
Rybarczyk, B J; Pereira, M; Simpson-Haidaris, P J (2000) Characterization of a monoclonal antibody, D73H, that maps to a highly conserved region on fibrinogen Bbeta chain. Thromb Haemost 84:43-8
Haidaris, C G; Fisher, D J; Gigliotti, F et al. (1998) Antigenic properties of recombinant glycosylated and nonglycosylated Pneumocystis carinii glycoprotein A polypeptides expressed in baculovirus-infected insect cells. Mol Biotechnol 9:91-7
Simpson-Haidaris, P J; Courtney, M A; Wright, T W et al. (1998) Induction of fibrinogen expression in the lung epithelium during Pneumocystis carinii pneumonia. Infect Immun 66:4431-9

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