Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050653-02
Application #
2226893
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1995-03-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Watanabe, T; Pakala, R; Katagiri, T et al. (2001) Angiotensin II and serotonin potentiate endothelin-1-induced vascular smooth muscle cell proliferation. J Hypertens 19:731-9
Watanabe, T; Pakala, R; Katagiri, T et al. (2001) Mildly oxidized low-density lipoprotein acts synergistically with angiotensin II in inducing vascular smooth muscle cell proliferation. J Hypertens 19:1065-73
Watanabe, T; Pakala, R; Katagiri, T et al. (2001) Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation. Atherosclerosis 155:37-44
Watanabe, T; Pakala, R; Katagiri, T et al. (2001) Serotonin potentiates angiotensin II--induced vascular smooth muscle cell proliferation. Atherosclerosis 159:269-79
Watanabe, T; Pakala, R; Koba, S et al. (2001) Lysophosphatidylcholine and reactive oxygen species mediate the synergistic effect of mildly oxidized LDL with serotonin on vascular smooth muscle cell proliferation. Circulation 103:1440-5
Pakala, R; Pakala, R; Sheng, W L et al. (2000) Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. Atherosclerosis 153:47-57
Koba, S; Pakala, R; Katagiri, T et al. (2000) Hyperlipemic-very low density lipoprotein, intermediate density lipoprotein and low density lipoprotein act synergistically with serotonin on vascular smooth muscle cell proliferation. Atherosclerosis 149:61-7
Pakala, R; Pakala, R; Sheng, W L et al. (1999) Eicosapentaenoic acid and docosahexaenoic acid block serotonin-induced smooth muscle cell proliferation. Arterioscler Thromb Vasc Biol 19:2316-22
Pakala, R; Benedict, C (1999) Synergy between thrombin and serotonin in inducing vascular smooth muscle cell proliferation. J Lab Clin Med 134:659-67
Thiagarajan, P; Le, A; Benedict, C R (1999) Beta(2)-glycoprotein I promotes the binding of anionic phospholipid vesicles by macrophages. Arterioscler Thromb Vasc Biol 19:2807-11

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