Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050724-03
Application #
2226997
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1994-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Pathology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Kapp, Judith A; Honjo, Kazuhito; Kapp, Linda M et al. (2007) Antigen, in the presence of TGF-beta, induces up-regulation of FoxP3gfp+ in CD4+ TCR transgenic T cells that mediate linked suppression of CD8+ T cell responses. J Immunol 179:2105-14
Kapp, Judith A; Honjo, Kazuhito; Kapp, Linda M et al. (2006) TCR transgenic CD8+ T cells activated in the presence of TGFbeta express FoxP3 and mediate linked suppression of primary immune responses and cardiac allograft rejection. Int Immunol 18:1549-62
Honjo, Kazuhito; Xu, Xiao Yan; Kapp, Judith A et al. (2004) Activation and migration of allo-peptide specific TCR transgenic T cells in cardiac allograft rejection. Cell Immunol 230:44-55
Honjo, Kazuhito; Yan Xu, Xiao; Kapp, Judith A et al. (2004) Evidence for cooperativity in the rejection of cardiac grafts mediated by CD4 TCR Tg T cells specific for a defined allopeptide. Am J Transplant 4:1762-8
Honjo, Kazuhito; Xu, Xiao yan; Bucy, R Pat (2004) CD4+ T-cell receptor transgenic T cells alone can reject vascularized heart transplants through the indirect pathway of alloantigen recognition. Transplantation 77:452-5
Honjo, K; Xu, X Y; Bucy, R P (2000) Heterogeneity of T cell clones specific for a single indirect alloantigenic epitope (I-Ab/H-2Kd54-68) that mediate transplant rejection. Transplantation 70:1516-24
Xu, X Y; Honjo, K; Devore-Carter, D et al. (1997) Immunosuppression by inhibition of cellular adhesion mediated by leukocyte function-associated antigen-1/intercellular adhesion molecule-1 in murine cardiac transplantation. Transplantation 63:876-85
Rogers, W O; Weaver, C T; Kraus, L A et al. (1997) Visualization of antigen-specific T cell activation and cytokine expression in vivo. J Immunol 158:649-57
Rice, J C; Bucy, R P (1995) Differences in the degree of depletion, rate of recovery, and the preferential elimination of naive CD4+ T cells by anti-CD4 monoclonal antibody (GK1.5) in young and aged mice. J Immunol 154:6644-54
Karr, L J; Panoskaltsis-Mortari, A; Li, J et al. (1995) In situ hybridization for cytokine mRNA with digoxigenin-labeled riboprobes. Sensitivity of detection and double label applications. J Immunol Methods 182:93-106

Showing the most recent 10 out of 12 publications