Kl and C-Kit: Role in Hematopoietic Stem Cell Hierarchy

Besmer, Peter

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL051031-03
• Application #: 2227409
• Study Section: Hematology Subcommittee 2 (HEM)
• Project Start: 1994-01-01
• Project End: 1997-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Sloan-Kettering Institute for Cancer Research
• DUNS #: 064931884
• City: New York
• State: NY
• Country: United States
• Zip Code: 10065

Publications

Deshpande, Shayu; Agosti, Valter; Manova, Katia et al. (2010) Kit ligand cytoplasmic domain is essential for basolateral sorting in vivo and has roles in spermatogenesis and hematopoiesis. Dev Biol 337:199-210

Joenje, H; Oostra, A B; Wijker, M et al. (1997) Evidence for at least eight Fanconi anemia genes. Am J Hum Genet 61:940-4

Vosseller, K; Stella, G; Yee, N S et al. (1997) c-kit receptor signaling through its phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling. Mol Biol Cell 8:909-22

Serve, H; Yee, N S; Stella, G et al. (1995) Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells. EMBO J 14:473-83