Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL051032-02
Application #
2227412
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1995-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Surgery
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Hoenicke, E M; Damiano Jr, R J (2001) Superior 12-hour heart preservation with pinacidil hyperpolarizing solution compared to University of Wisconsin solution. J Heart Lung Transplant 20:1106-14
Sun, X; Ducko, C T; Hoenicke, E M et al. (2000) Mechanisms responsible for cell volume regulation during hyperkalemic cardioplegic arrest. Ann Thorac Surg 70:633-8
Hoenicke, E M; Sun, X; Strange Jr, R G et al. (2000) Donor heart preservation with a novel hyperpolarizing solution: superior protection compared with University of Wisconsin solution. J Thorac Cardiovasc Surg 120:746-54
Stephenson Jr, E R; Jayawant, A M; Baumgarten, C M et al. (2000) Cardioplegia-induced cell swelling: prevention by normothermic infusion. Ann Thorac Surg 69:1393-8
Ducko, C T; Stephenson Jr, E R; Jayawant, A M et al. (2000) Potassium channel openers: are they effective as pretreatment or additives to cardioplegia? Ann Thorac Surg 69:1363-8
Jayawant, A M; Stephenson Jr, E R; Matte, G S et al. (1999) Potassium-channel opener cardioplegia is superior to St. Thomas' solution in the intact animal. Ann Thorac Surg 68:67-74
Lawton, J S; Hsia, P W; Damiano Jr, R J (1998) The adenosine-triphosphate-sensitive potassium-channel opener pinacidil is effective in blood cardioplegia. Ann Thorac Surg 66:768-73
Jayawant, A M; Stephenson Jr, E R; Baumgarten, C M et al. (1998) Prevention of cell swelling with low chloride St. Thomas' Hospital solution improves postischemic myocardial recovery. J Thorac Cardiovasc Surg 115:1196-202
Jayawant, A M; Damiano Jr, R J (1998) The superiority of pinacidil over adenosine cardioplegia in blood-perfused isolated hearts. Ann Thorac Surg 66:1329-35;discussion 1335-6
Shaffer, R F; Baumgarten, C M; Damiano Jr, R J (1998) Prevention of cellular edema directly caused by hypothermic cardioplegia: studies in isolated human and rabbit atrial myocytes. J Thorac Cardiovasc Surg 115:1189-95

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