Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL051043-01A3
Application #
2227427
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1996-05-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Ashton, Anthony W; Cheng, Yan; Helisch, Armin et al. (2004) Thromboxane A2 receptor agonists antagonize the proangiogenic effects of fibroblast growth factor-2: role of receptor internalization, thrombospondin-1, and alpha(v)beta3. Circ Res 94:735-42
Ashton, Anthony W; Ware, J Anthony (2004) Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration. Circ Res 95:372-9
Ashton, Anthony W; Ware, Gabriel M; Kaul, Dhananjaya K et al. (2003) Inhibition of tumor necrosis factor alpha-mediated NFkappaB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands. J Biol Chem 278:11858-66
Colombo, Paolo C; Ashton, Anthony W; Celaj, Sulejman et al. (2002) Biopsy coupled to quantitative immunofluorescence: a new method to study the human vascular endothelium. J Appl Physiol 92:1331-8
Murakami, Masahiro; Horowitz, Arie; Tang, Shaoqing et al. (2002) Protein kinase C (PKC) delta regulates PKCalpha activity in a Syndecan-4-dependent manner. J Biol Chem 277:20367-71
Gao, Y; Tang, S; Zhou, S et al. (2001) The thromboxane A2 receptor activates mitogen-activated protein kinase via protein kinase C-dependent Gi coupling and Src-dependent phosphorylation of the epidermal growth factor receptor. J Pharmacol Exp Ther 296:426-33
Itoh, H; Yamamura, S; Ware, J A et al. (2001) Differential effects of protein kinase C on human vascular smooth muscle cell proliferation and migration. Am J Physiol Heart Circ Physiol 281:H359-70
Harrington, E O; Doyle, K E; Brunelle, J L et al. (2000) Endothelial proliferation, migration, and differentiation are blunted by conditionally expressed protein kinase C pseudosubstrate peptides. Biochem Biophys Res Commun 271:499-508
Gao, Y; Yokota, R; Tang, S et al. (2000) Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2). Circ Res 87:739-45
Shizukuda, Y; Helisch, A; Yokota, R et al. (1999) Downregulation of protein kinase cdelta activity enhances endothelial cell adaptation to hypoxia. Circulation 100:1909-16

Showing the most recent 10 out of 15 publications