Cloning of Cardiac Transcription Factors

Izumo, Seigo

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL051253-03
• Application #: 2329423
• Study Section: Cardiovascular and Pulmonary Research A Study Section (CVA)
• Project Start: 1994-01-01
• Project End: 1998-12-31
• Budget Start: 1996-09-23
• Budget End: 1996-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Michigan Ann Arbor
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 791277940
• City: Ann Arbor
• State: MI
• Country: United States
• Zip Code: 48109

Publications

Kasahara, H; Usheva, A; Ueyama, T et al. (2001) Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein. J Biol Chem 276:4570-80

Tanaka, M; Komuro, I; Inagaki, H et al. (2000) Nkx3.1, a murine homolog of Ddrosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands. Dev Dyn 219:248-60

Kasahara, H; Lee, B; Schott, J J et al. (2000) Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease. J Clin Invest 106:299-308

Kasahara, H; Izumo, S (1999) Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tisue-specifying homeobox gene product Csx/Nkx2.5. Mol Cell Biol 19:526-36

Tanaka, M; Wechsler, S B; Lee, I W et al. (1999) Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5. Development 126:1439-50

Russell, M W; Kemp, P; Wang, L et al. (1998) Molecular cloning of the human HAND2 gene. Biochim Biophys Acta 1443:393-9