Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051650-03
Application #
2228546
Study Section
Special Emphasis Panel (ZHL1-CSR-B (S3))
Project Start
1993-12-22
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Kralovics, R; Sokol, L; Prchal, J T (1998) Absence of polycythemia in a child with a unique erythropoietin receptor mutation in a family with autosomal dominant primary polycythemia. J Clin Invest 102:124-9
Stopka, T; Zivny, J H; Goldwasser, E et al. (1998) Guinea pig serum erythropoietin (EPO) selectively stimulates guinea pig erythroid progenitors: human or mouse erythroid progenitors do not form erythroid burst-forming unit colonies in response to guinea pig serum EPO. Exp Hematol 26:910-4
Stopka, T; Zivny, J H; Stopkova, P et al. (1998) Human hematopoietic progenitors express erythropoietin. Blood 91:3766-72
Chen, Q; Lentz, B R (1997) Fluorescence resonance energy transfer study of shape changes in membrane-bound bovine prothrombin and meizothrombin. Biochemistry 36:4701-11
Kralovics, R; Indrak, K; Stopka, T et al. (1997) Two new EPO receptor mutations: truncated EPO receptors are most frequently associated with primary familial and congenital polycythemias. Blood 90:2057-61
Kralovics, R; Sokol, L; Broxson Jr, E H et al. (1997) The erythropoietin receptor gene is not linked with the polycythemia phenotype in a family with autosomal dominant primary polycythemia. Proc Assoc Am Physicians 109:580-5
Sergeyeva, A; Gordeuk, V R; Tokarev, Y N et al. (1997) Congenital polycythemia in Chuvashia. Blood 89:2148-54
Jenkins, M M; Prchal, J T (1997) A high-frequency polymorphism of NADH-cytochrome b5 reductase in African-Americans. Hum Genet 99:248-50
Gregg, X T; Prchal, J T (1997) Erythropoietin receptor mutations and human disease. Semin Hematol 34:70-6
Chen, Q; Lord, S T; Lentz, B R (1997) Partially purified Echis carinatus venom cleaves active-site-mutated bovine prothrombin at two sites. Thromb Res 85:369-75

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