Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051824-04
Application #
2228787
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1993-06-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Georgetown University
Department
Physiology
Type
Schools of Dentistry
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057

  Publications

Kitazawa, Toshio (2010) G protein-mediated Ca²+-sensitization of CPI-17 phosphorylation in arterial smooth muscle. Biochem Biophys Res Commun 401:75-8
Woodsome, Terence P; Polzin, Atsuko; Kitazawa, Kazuyo et al. (2006) Agonist- and depolarization-induced signals for myosin light chain phosphorylation and force generation of cultured vascular smooth muscle cells. J Cell Sci 119:1769-80
Kitazawa, Toshio; Polzin, Atsuko N; Eto, Masumi (2004) CPI-17-deficient smooth muscle of chicken. J Physiol 557:515-28
Eto, Masumi; Kitazawa, Toshio; Brautigan, David L (2004) Phosphoprotein inhibitor CPI-17 specificity depends on allosteric regulation of protein phosphatase-1 by regulatory subunits. Proc Natl Acad Sci U S A 101:8888-93
Kitazawa, Toshio; Eto, Masumi; Woodsome, Terence P et al. (2003) Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle. J Physiol 546:879-89
Eto, M; Kitazawa, T; Yazawa, M et al. (2001) Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms. J Biol Chem 276:29072-8
Woodsome, T P; Eto, M; Everett, A et al. (2001) Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle. J Physiol 535:553-64
Kitazawa, T; Eto, M; Woodsome, T P et al. (2000) Agonists trigger G protein-mediated activation of the CPI-17 inhibitor phosphoprotein of myosin light chain phosphatase to enhance vascular smooth muscle contractility. J Biol Chem 275:9897-900
Kitazawa, T; Takizawa, N; Ikebe, M et al. (1999) Reconstitution of protein kinase C-induced contractile Ca2+ sensitization in triton X-100-demembranated rabbit arterial smooth muscle. J Physiol 520 Pt 1:139-52
Murahashi, T; Fujita, A; Kitazawa, T (1999) Ca2+ -induced Ca2+ desensitization of myosin light chain phosphorylation and contraction in phasic smooth muscle. Mol Cell Biochem 190:91-8

Showing the most recent 10 out of 14 publications