Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL051912-06A1
Application #
6198536
Study Section
Special Emphasis Panel (ZRG1-ALTX-1 (01))
Project Start
1994-12-01
Project End
2005-06-30
Budget Start
2000-07-20
Budget End
2001-06-30
Support Year
6
Fiscal Year
2000
Total Cost
$410,000
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Wang, Jian; Shimoda, Larissa A; Sylvester, J T (2012) Ca2+ responses of pulmonary arterial myocytes to acute hypoxia require release from ryanodine and inositol trisphosphate receptors in sarcoplasmic reticulum. Am J Physiol Lung Cell Mol Physiol 303:L161-8
Sylvester, J T; Shimoda, Larissa A; Aaronson, Philip I et al. (2012) Hypoxic pulmonary vasoconstriction. Physiol Rev 92:367-520
Weigand, Letitia; Shimoda, Larissa A; Sylvester, J T (2011) Enhancement of myofilament calcium sensitivity by acute hypoxia in rat distal pulmonary arteries. Am J Physiol Lung Cell Mol Physiol 301:L380-7
Lu, Wenju; Wang, Jian; Shimoda, Larissa A et al. (2008) Differences in STIM1 and TRPC expression in proximal and distal pulmonary arterial smooth muscle are associated with differences in Ca2+ responses to hypoxia. Am J Physiol Lung Cell Mol Physiol 295:L104-13
Whitman, E Miles; Pisarcik, Sarah; Luke, Trevor et al. (2008) Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes. Am J Physiol Lung Cell Mol Physiol 294:L309-18
Wang, Jian; Weigand, Letitia; Foxson, Joshua et al. (2007) Ca2+ signaling in hypoxic pulmonary vasoconstriction: effects of myosin light chain and Rho kinase antagonists. Am J Physiol Lung Cell Mol Physiol 293:L674-85
Wang, Jian; Weigand, Letitia; Lu, Wenju et al. (2006) Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells. Circ Res 98:1528-37
Shimoda, Larissa A; Wang, Jian; Sylvester, J T (2006) Ca2+ channels and chronic hypoxia. Microcirculation 13:657-70
Wang, Jian; Shimoda, Larissa A; Weigand, Letitia et al. (2005) Acute hypoxia increases intracellular [Ca2+] in pulmonary arterial smooth muscle by enhancing capacitative Ca2+ entry. Am J Physiol Lung Cell Mol Physiol 288:L1059-69
Wang, Jian; Weigand, Letitia; Wang, Wenqian et al. (2005) Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery. Am J Physiol Lung Cell Mol Physiol 288:L1049-58

Showing the most recent 10 out of 25 publications