Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051930-02
Application #
2228970
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1995-07-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Freed, Arthur N; McCulloch, Sharron; Meyers, Teresa et al. (2003) Neurokinins modulate hyperventilation-induced bronchoconstriction in canine peripheral airways. Am J Respir Crit Care Med 167:1102-8
Davis, Michael S; Schofield, Brian; Freed, Arthur N (2003) Repeated peripheral airway hyperpnea causes inflammation and remodeling in dogs. Med Sci Sports Exerc 35:608-16
Suzuki, Ryoichi; Freed, Arthur N (2002) Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. Am J Respir Crit Care Med 165:27-33
Davis, Michael S; McCulloch, Sharron; Myers, Teresa et al. (2002) Eicosanoids modulate hyperpnea-induced late phase airway obstruction and hyperreactivity in dogs. Respir Physiol 129:357-65
Suzuki, R; Freed, A N (2000) Hypertonic saline aerosol increases airway reactivity in the canine lung periphery. J Appl Physiol 89:2139-46
Freed, A N; McCulloch, S; Wang, Y (2000) Eicosanoid and muscarinic receptor blockade abolishes hyperventilation-induced bronchoconstriction. J Appl Physiol 89:1949-55
Suzuki, R; Freed, A N (2000) Heparin inhibits eicosanoid metabolism and hyperventilation-induced bronchoconstriction in dogs. Am J Respir Crit Care Med 161:1850-4
Freed, A N; Davis, M S (1999) Hyperventilation with dry air increases airway surface fluid osmolality in canine peripheral airways. Am J Respir Crit Care Med 159:1101-7
Freed, A N; Wang, Y; McCulloch, S et al. (1999) Mucosal injury and eicosanoid kinetics during hyperventilation-induced bronchoconstriction. J Appl Physiol 87:1724-33
Davis, M S; Freed, A N (1999) Repetitive hyperpnoea causes peripheral airway obstruction and eosinophilia. Eur Respir J 14:57-62

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