Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051967-04
Application #
2029079
Study Section
Special Emphasis Panel (ZHL1-CSR-N (S3))
Project Start
1993-09-30
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Firmani, Marcia A; Riley, Lee W (2002) Mycobacterium tuberculosis CDC1551 is resistant to reactive nitrogen and oxygen intermediates in vitro. Infect Immun 70:3965-8
Firmani, Marcia A; Riley, Lee W (2002) Reactive nitrogen intermediates have a bacteriostatic effect on Mycobacterium tuberculosis in vitro. J Clin Microbiol 40:3162-6
Stewart, G R; Ehrt, S; Riley, L W et al. (2000) Deletion of the putative antioxidant noxR1 does not alter the virulence of Mycobacterium tuberculosis H37Rv. Tuber Lung Dis 80:237-42
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Ruan, J; St John, G; Ehrt, S et al. (1999) noxR3, a novel gene from Mycobacterium tuberculosis, protects Salmonella typhimurium from nitrosative and oxidative stress. Infect Immun 67:3276-83
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Chen, L; Xie, Q W; Nathan, C (1998) Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates. Mol Cell 1:795-805
Karupiah, G; Chen, J H; Mahalingam, S et al. (1998) Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med 188:1541-6
Karupiah, G; Chen, J H; Nathan, C F et al. (1998) Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection. J Virol 72:7703-6
Friedman, C R; Quinn, G C; Kreiswirth, B N et al. (1997) Widespread dissemination of a drug-susceptible strain of Mycobacterium tuberculosis. J Infect Dis 176:478-84

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