Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052005-02
Application #
2229095
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1994-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
San Diego State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
073371346
City
San Diego
State
CA
Country
United States
Zip Code
92182
Du, E Z; Fleming, J F; Wang, S L et al. (1999) Translocation-arrested apolipoprotein B evades proteasome degradation via a sterol-sensitive block in ubiquitin conjugation. J Biol Chem 274:1856-62
Fleming, J F; Spitsen, G M; Hui, T Y et al. (1999) Chinese hamster ovary cells require the coexpression of microsomal triglyceride transfer protein and cholesterol 7alpha-hydroxylase for the assembly and secretion of apolipoprotein B-containing lipoproteins. J Biol Chem 274:9509-14
Trawick, J D; Wang, S L; Bell, D et al. (1997) Transcriptional induction of cholesterol 7alpha-hydroxylase by dexamethasone in L35 hepatoma cells requires sulfhydryl reducing agents. J Biol Chem 272:3099-102
Davis, R A (1997) Evolution of processes and regulators of lipoprotein synthesis: from birds to mammals. J Nutr 127:795S-800S
Wang, S L; Du, E Z; Martin, T D et al. (1997) Coordinate regulation of lipogenesis, the assembly and secretion of apolipoprotein B-containing lipoproteins by sterol response element binding protein 1. J Biol Chem 272:19351-8
Moore, G L; Drevon, C A; Machleder, D et al. (1997) Expression of human cholesterol 7alpha-hydroxylase in atherosclerosis-susceptible mice via adenovirus infection. Biochem J 324 ( Pt 3):863-7
Dueland, S; France, D; Wang, S L et al. (1997) Cholesterol 7alpha-hydroxylase influences the expression of hepatic apoA-I in two inbred mouse strains displaying different susceptibilities to atherosclerosis and in hepatoma cells. J Lipid Res 38:1445-53
Trawick, J D; Lewis, K D; Dueland, S et al. (1996) Rat hepatoma L35 cells, a liver-differentiated cell line, display resistance to bile acid repression of cholesterol 7 alpha-hydroxylase. J Lipid Res 37:588-98
Song, W J; Van Keuren, M L; Drabkin, H A et al. (1996) Assignment of the human slow twitch skeletal muscle/cardiac troponin C gene (TNNC1) to human chromosome 3p21.3-->3p14.3 using somatic cell hybrids. Cytogenet Cell Genet 75:36-7