Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052134-03
Application #
2229320
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Jay, Patrick Y; Bielinska, Malgorzata; Erlich, Jonathan M et al. (2007) Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects. Dev Biol 301:602-14
Bielinska, Malgorzata; Seehra, Amrita; Toppari, Jorma et al. (2007) GATA-4 is required for sex steroidogenic cell development in the fetal mouse. Dev Dyn 236:203-13
Bielinska, Malgorzata; Jay, Patrick Y; Erlich, Jonathan M et al. (2007) Molecular genetics of congenital diaphragmatic defects. Ann Med 39:261-74
Heikinheimo, M; Ermolaeva, M; Bielinska, M et al. (1997) Expression and hormonal regulation of transcription factors GATA-4 and GATA-6 in the mouse ovary. Endocrinology 138:3505-14
Narita, N; Bielinska, M; Wilson, D B (1997) Cardiomyocyte differentiation by GATA-4-deficient embryonic stem cells. Development 124:3755-64
Narita, N; Bielinska, M; Wilson, D B (1997) Wild-type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouse. Dev Biol 189:270-4
Bielinska, M; Narita, N; Heikinheimo, M et al. (1996) Erythropoiesis and vasculogenesis in embryoid bodies lacking visceral yolk sac endoderm. Blood 88:3720-30
Bielinska, M; Wilson, D B (1995) Regulation of J6 gene expression by transcription factor GATA-4. Biochem J 307 ( Pt 1):183-9
White, R A; Dowler, L L; Pasztor, L M et al. (1995) Assignment of the transcription factor GATA4 gene to human chromosome 8 and mouse chromosome 14: Gata4 is a candidate gene for Ds (disorganization). Genomics 27:20-6
Ip, H S; Wilson, D B; Heikinheimo, M et al. (1994) The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Mol Cell Biol 14:7517-26

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