Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052211-03
Application #
2229462
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1995-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Weber, D S; Lombard, J H (2000) Elevated salt intake impairs dilation of rat skeletal muscle resistance arteries via ANG II suppression. Am J Physiol Heart Circ Physiol 278:H500-6
Frisbee, J C; Lombard, J H (2000) Short-term angiotensin converting enzyme inhibition reduces basal tone and dilator reactivity in skeletal muscle arterioles. Am J Hypertens 13:389-95
Frisbee, J C; Falck, J R; Lombard, J H (2000) Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension. Am J Physiol Heart Circ Physiol 278:H1517-26
Weber, D S; Frisbee, J C; Lombard, J H (1999) Selective potentiation of angiotensin-induced constriction of skeletal muscle resistance arteries by chronic elevations in dietary salt intake. Microvasc Res 57:310-9
Frisbee, J C; Weber, D S; Lombard, J H (1999) Chronic captopril administration decreases vasodilator responses in skeletal muscle arterioles. Am J Hypertens 12:705-15
Frisbee, J C; Lombard, J H (1999) Acute elevations in salt intake and reduced renal mass hypertension compromise arteriolar dilation in rat cremaster muscle. Microvasc Res 57:273-83
Frisbee, J C; Lombard, J H (1999) Development and reversibility of altered skeletal muscle arteriolar structure and reactivity with high salt diet and reduced renal mass hypertension. Microcirculation 6:215-25
Lombard, J H; Liu, Y; Fredricks, K T et al. (1999) Electrical and mechanical responses of rat middle cerebral arteries to reduced PO2 and prostacyclin. Am J Physiol 276:H509-16
Liu, Y; Fredricks, K T; Roman, R J et al. (1997) Response of resistance arteries to reduced PO2 and vasodilators during hypertension and elevated salt intake. Am J Physiol 273:H869-77