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Porter, J E; Perez, D M (2000) Influence of a lysine 331 counterion on the pK(a) of aspartic acid 125: evidence for a salt-bridge interaction and role in alpha(1b)-adrenergic receptor activation. J Pharmacol Exp Ther 292:440-8
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Porter, J E; Perez, D M (1999) Characteristics for a salt-bridge switch mutation of the alpha(1b) adrenergic receptor. Altered pharmacology and rescue of constitutive activity. J Biol Chem 274:34535-8
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Waugh, D J; Gaivin, R J; Damron, D S et al. (1999) Binding, partial agonism, and potentiation of alpha(1)-adrenergic receptor function by benzodiazepines: A potential site of allosteric modulation. J Pharmacol Exp Ther 291:1164-71
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Zuscik, M J; Piascik, M T; Perez, D M (1999) Cloning, cell-type specificity, and regulatory function of the mouse alpha(1B)-adrenergic receptor promoter. Mol Pharmacol 56:1288-97
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Perez, D M; Hwa, J; Zhao, M M et al. (1998) Molecular mechanisms of ligand binding and activation in alpha 1-adrenergic receptors. Adv Pharmacol 42:398-403
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Porter, J E; Edelmann, S E; Waugh, D J et al. (1998) The agonism and synergistic potentiation of weak partial agonists by triethylamine in alpha 1-adrenergic receptor activation: evidence for a salt bridge as the initiating process. Mol Pharmacol 53:766-71
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Zhao, M M; Gaivin, R J; Perez, D M (1998) The third extracellular loop of the beta2-adrenergic receptor can modulate receptor/G protein affinity. Mol Pharmacol 53:524-9
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Hwa, J; Gaivin, R; Porter, J E et al. (1997) Synergism of constitutive activity in alpha 1-adrenergic receptor activation. Biochemistry 36:633-9
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Zhao, M M; Hwa, J; Perez, D M (1996) Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding. Mol Pharmacol 50:1118-26
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Hwa, J; Perez, D M (1996) The unique nature of the serine interactions for alpha 1-adrenergic receptor agonist binding and activation. J Biol Chem 271:6322-7
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