Mechanisms of Cytokine Injury to Myocardium in Surgery

McGowan, Francis X.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 1R01HL052589-01A2
• Application #: 2230050
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Project Start: 1996-03-01
• Project End: 2000-02-29
• Budget Start: 1996-03-01
• Budget End: 1997-02-28
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Children's Hospital Boston
• DUNS #: 076593722
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02115

Publications

Allan, Catherine K; Newburger, Jane W; McGrath, Ellen et al. (2010) The relationship between inflammatory activation and clinical outcome after infant cardiopulmonary bypass. Anesth Analg 111:1244-51

Kitahori, Kazuo; He, Huamei; Kawata, Mitsuhiro et al. (2009) Development of left ventricular diastolic dysfunction with preservation of ejection fraction during progression of infant right ventricular hypertrophy. Circ Heart Fail 2:599-607

Gonnella, Patricia A; Del Nido, Pedro J; McGowan, Francis X (2009) Oral tolerization with cardiac myosin peptide (614-629) ameliorates experimental autoimmune myocarditis: role of STAT 6 genes in BALB/CJ mice. J Clin Immunol 29:434-43

Gonnella, Patricia A; Waldner, Hanspeter; Del Nido, Pedro J et al. (2008) Inhibition of experimental autoimmune myocarditis: peripheral deletion of TcR Vbeta 8.1, 8.2+ CD4+ T cells in TLR-4 deficient mice. J Autoimmun 31:180-7

Sawasdiwipachai, Prasert; Laussen, Peter C; McGowan, Francis X et al. (2007) Cardiac arrest after neuromuscular blockade reversal in a heart transplant infant. Anesthesiology 107:663-5

Choi, Yeong-Hoon; Stamm, Christof; Hammer, Peter E et al. (2006) Cardiac conduction through engineered tissue. Am J Pathol 169:72-85

Friehs, Ingeborg; Moran, Adrian M; Stamm, Christof et al. (2004) Promoting angiogenesis protects severely hypertrophied hearts from ischemic injury. Ann Thorac Surg 77:2004-10; discussion 2011

Cowan, Douglas B; Jones, Mara; Garcia, Lina M et al. (2003) Hypoxia and stretch regulate intercellular communication in vascular smooth muscle cells through reactive oxygen species formation. Arterioscler Thromb Vasc Biol 23:1754-60

Friehs, Ingeborg; Cao-Danh, Hung; Stamm, Christof et al. (2003) Postnatal increase in insulin-sensitive glucose transporter expression is associated with improved recovery of postischemic myocardial function. J Thorac Cardiovasc Surg 126:263-71

Chanani, Nikhil K; Cowan, Douglas B; Takeuchi, Koh et al. (2002) Differential effects of amrinone and milrinone upon myocardial inflammatory signaling. Circulation 106:I284-9