Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052671-02
Application #
2230201
Study Section
Special Emphasis Panel (ZRG2-PHY (02))
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rush University Medical Center
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612
Morgan, Deri; DeCoursey, Thomas E (2007) Analysis of electrophysiological properties and responses of neutrophils. Methods Mol Biol 412:139-75
Morgan, Deri; Cherny, Vladimir V; Finnegan, Alison et al. (2007) Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. J Physiol 579:327-44
DeCoursey, Thomas E; Cherny, Vladimir V (2007) Pharmacology of voltage-gated proton channels. Curr Pharm Des 13:2400-20
Femling, Jon K; Cherny, Vladimir V; Morgan, Deri et al. (2006) The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels. J Gen Physiol 127:659-72
Murphy, Ricardo; DeCoursey, Thomas E (2006) Charge compensation during the phagocyte respiratory burst. Biochim Biophys Acta 1757:996-1011
Decoursey, T E; Ligeti, E (2005) Regulation and termination of NADPH oxidase activity. Cell Mol Life Sci 62:2173-93
Morgan, Deri; Cherny, Vladimir V; Murphy, Ricardo et al. (2005) The pH dependence of NADPH oxidase in human eosinophils. J Physiol 569:419-31
Murphy, Ricardo; Cherny, Vladimir V; Morgan, Deri et al. (2005) Voltage-gated proton channels help regulate pHi in rat alveolar epithelium. Am J Physiol Lung Cell Mol Physiol 288:L398-408
Decoursey, Thomas E (2003) Voltage-gated proton channels and other proton transfer pathways. Physiol Rev 83:475-579
Cherny, Vladimir V; Murphy, Ricardo; Sokolov, Valerij et al. (2003) Properties of single voltage-gated proton channels in human eosinophils estimated by noise analysis and by direct measurement. J Gen Physiol 121:615-28

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