Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052810-02
Application #
2230434
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Emory University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322

  Publications

Ediger, T L; Schulte, N A; Murphy, T J et al. (2003) Transcription factor activation and mitogenic synergism in airway smooth muscle cells. Eur Respir J 21:759-69
Wang, X; Murphy, T J (2000) The inducible cAMP early repressor ICERIIgamma inhibits CREB and AP-1 transcription but not AT1 receptor gene expression in vascular smooth muscle cells. Mol Cell Biochem 212:111-9
Xu, K; Murphy, T J (2000) Reconstitution of angiotensin receptor mRNA down-regulation in vascular smooth muscle. Post-transcriptional control by protein kinase a but not mitogenic signaling directed by the 5'-untranslated region. J Biol Chem 275:7604-11
Abbott, K L; Robida, A M; Davis, M E et al. (2000) Differential regulation of vascular smooth muscle nuclear factor kappa-B by G alpha q-coupled and cytokine receptors. J Mol Cell Cardiol 32:391-403
Robida, A M; Xu, K; Ellington, M L et al. (2000) Cyclosporin A selectively inhibits mitogen-induced cyclooxygenase-2 gene transcription in vascular smooth muscle cells. Mol Pharmacol 58:701-8
Xu, K; Robida, A M; Murphy, T J (2000) Immediate-early MEK-1-dependent stabilization of rat smooth muscle cell cyclooxygenase-2 mRNA by Galpha(q)-coupled receptor signaling. J Biol Chem 275:23012-9
Abbott, K L; Loss 2nd, J R; Robida, A M et al. (2000) Evidence that Galpha(q)-coupled receptor-induced interleukin-6 mRNA in vascular smooth muscle cells involves the nuclear factor of activated T cells. Mol Pharmacol 58:946-53
Zhong, H; Murphy, T J; Minneman, K P (2000) Activation of signal transducers and activators of transcription by alpha(1A)-adrenergic receptor stimulation in PC12 cells. Mol Pharmacol 57:961-7
Boss, V; Wang, X; Koppelman, L F et al. (1998) Histamine induces nuclear factor of activated T cell-mediated transcription and cyclosporin A-sensitive interleukin-8 mRNA expression in human umbilical vein endothelial cells. Mol Pharmacol 54:264-72
Wang, X; Murphy, T J (1998) Inhibition of cyclic AMP-dependent kinase by expression of a protein kinase inhibitor/enhanced green fluorescent fusion protein attenuates angiotensin II-induced type 1 AT1 receptor mRNA down-regulation in vascular smooth muscle cells. Mol Pharmacol 54:514-24

Showing the most recent 10 out of 13 publications