Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053031-03
Application #
2230770
Study Section
Special Emphasis Panel (ZHL1-CSR-S (M1))
Project Start
1994-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
Lieberthal, Wilfred; Fuhro, Robert; Alam, Hasan et al. (2002) Comparison of the effects of a 50% exchange-transfusion with albumin, hetastarch, and modified hemoglobin solutions. Shock 17:61-9
Bergin, E; Levine, J S; Koh, J S et al. (2000) Mouse proximal tubular cell-cell adhesion inhibits apoptosis by a cadherin-dependent mechanism. Am J Physiol Renal Physiol 278:F758-68
Lieberthal, W; Fuhro, R; Freedman, J E et al. (1999) O-raffinose cross-linking markedly reduces systemic and renal vasoconstrictor effects of unmodified human hemoglobin. J Pharmacol Exp Ther 288:1278-87
Iglesias, J; Abernethy, V E; Wang, Z et al. (1999) Albumin is a major serum survival factor for renal tubular cells and macrophages through scavenging of ROS. Am J Physiol 277:F711-22
Zoeller, R A; Lake, A C; Nagan, N et al. (1999) Plasmalogens as endogenous antioxidants: somatic cell mutants reveal the importance of the vinyl ether. Biochem J 338 ( Pt 3):769-76
Lieberthal, W; Menza, S A; Levine, J S (1998) Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. Am J Physiol 274:F315-27
Koh, J S; Lieberthal, W; Heydrick, S et al. (1998) Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway. J Clin Invest 102:716-27
Lieberthal, W; Triaca, V; Koh, J S et al. (1998) Role of superoxide in apoptosis induced by growth factor withdrawal. Am J Physiol 275:F691-702
Lieberthal, W; Koh, J S; Levine, J S (1998) Necrosis and apoptosis in acute renal failure. Semin Nephrol 18:505-18
Lieberthal, W; McKenney, J B; Kiefer, C R et al. (1997) Beta1 integrin-mediated adhesion between renal tubular cells after anoxic injury. J Am Soc Nephrol 8:175-83

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