Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053515-02
Application #
2231483
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1995-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hubel, Kai; Rodger, Elin; Gaviria, J Milton et al. (2005) Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte-colony-stimulating factor. Transfusion 45:1876-89
Price, T H; Bowden, R A; Boeckh, M et al. (2000) Phase I/II trial of neutrophil transfusions from donors stimulated with G-CSF and dexamethasone for treatment of patients with infections in hematopoietic stem cell transplantation. Blood 95:3302-9
Gaviria, J M; van Burik, J A; Dale, D C et al. (1999) Comparison of interferon-gamma, granulocyte colony-stimulating factor, and granulocyte-macrophage colony-stimulating factor for priming leukocyte-mediated hyphal damage of opportunistic fungal pathogens. J Infect Dis 179:1038-41
Gaviria, J M; van Burik, J A; Dale, D C et al. (1999) Modulation of neutrophil-mediated activity against the pseudohyphal form of Candida albicans by granulocyte colony-stimulating factor (G-CSF) administered in vivo. J Infect Dis 179:1301-4
Dale, D C (1998) The discovery, development and clinical applications of granulocyte colony-stimulating factor. Trans Am Clin Climatol Assoc 109:27-36;discussion 36-8
Dale, D C; Liles, W C; Llewellyn, C et al. (1998) Effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) on neutrophil kinetics and function in normal human volunteers. Am J Hematol 57:7-15
Bauer, T R; Schwartz, B R; Liles, W C et al. (1998) Retroviral-mediated gene transfer of the leukocyte integrin CD18 into peripheral blood CD34+ cells derived from a patient with leukocyte adhesion deficiency type 1. Blood 91:1520-6
Dale, D C; Liles, W C; Llewellyn, C et al. (1998) Neutrophil transfusions: kinetics and functions of neutrophils mobilized with granulocyte-colony-stimulating factor and dexamethasone. Transfusion 38:713-21
Liles, W C; Huang, J E; van Burik, J A et al. (1997) Granulocyte colony-stimulating factor administered in vivo augments neutrophil-mediated activity against opportunistic fungal pathogens. J Infect Dis 175:1012-5
Dale, D C; Liles, W C; Price, T H (1997) Renewed interest in granulocyte transfusion therapy. Br J Haematol 98:497-501

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