Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053665-03
Application #
2231707
Study Section
Special Emphasis Panel (ZHL1-CSR-K (S1))
Project Start
1994-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Gnatenko, Dmitri V; Zhu, Wei; Xu, Xiao et al. (2010) Class prediction models of thrombocytosis using genetic biomarkers. Blood 115:7-14
Damon, Andrea L; Scudder, Lesley E; Gnatenko, Dmitri V et al. (2008) Altered bioavailability of platelet-derived factor VIII during thrombocytosis reverses phenotypic efficacy in haemophilic mice. Thromb Haemost 100:1111-22
Gnatenko, Dmitri V; Perrotta, Peter L; Bahou, Wadie F (2006) Proteomic approaches to dissect platelet function: Half the story. Blood 108:3983-91
Rosenfeldt, Mathias T; Valentino, Michael; Labruzzo, Salvatore et al. (2005) The organomercurial 4-aminophenylmercuric acetate, independent of matrix metalloproteinases, induces dose-dependent activation/inhibition of platelet aggregation. Thromb Haemost 93:326-30
Bahou, Wadie F; Scudder, Lesley; Rubenstein, David et al. (2004) A shear-restricted pathway of platelet procoagulant activity is regulated by IQGAP1. J Biol Chem 279:22571-7
Gnatenko, Dmitri V; Wu, Yong; Jesty, Jolyon et al. (2004) Expression of therapeutic levels of factor VIII in hemophilia A mice using a novel adeno/adeno-associated hybrid virus. Thromb Haemost 92:317-27
Bahou, Wadie F; Gnatenko, Dmitri V (2004) Platelet transcriptome: the application of microarray analysis to platelets. Semin Thromb Hemost 30:473-84
Schmidt, Valentina A; Scudder, Lesley; Devoe, Craig E et al. (2003) IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. Blood 101:3021-8
Gnatenko, Dmitri V; Dunn, John J; McCorkle, Sean R et al. (2003) Transcript profiling of human platelets using microarray and serial analysis of gene expression. Blood 101:2285-93
Sandalon, Z; Gnatenko, D V; Bahou, W F et al. (2000) Adeno-associated virus (AAV) Rep protein enhances the generation of a recombinant mini-adenovirus (Ad) utilizing an Ad/AAV hybrid virus. J Virol 74:10381-9

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