Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL054143-02
Application #
2232398
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1995-04-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Martin, Gilles; O'Connell, Robert J; Pietrzykowski, Andrzej Z et al. (2008) Interleukin-4 activates large-conductance, calcium-activated potassium (BKCa) channels in human airway smooth muscle cells. Exp Physiol 93:908-18
Ethier, Michael F; Madison, J Mark (2006) Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells. Am J Respir Cell Mol Biol 35:496-502
Ethier, Michael F; Madison, J Mark (2006) IL-4 inhibits calcium transients in bovine trachealis cells by a ryanodine receptor-dependent mechanism. FASEB J 20:154-6
Ethier, Michael F; Cappelluti, Erika; Madison, J Mark (2005) Mechanisms of interleukin-4 effects on calcium signaling in airway smooth muscle cells. J Pharmacol Exp Ther 313:127-33
Madison, J Mark (2003) Migration of airway smooth muscle cells. Am J Respir Cell Mol Biol 29:8-11
Ethier, M F; Madison, J M (2002) LY294002, but not wortmannin, increases intracellular calcium and inhibits calcium transients in bovine and human airway smooth muscle cells. Cell Calcium 32:31-8
Ethier, M F; Yamaguchi, H; Madison, J M (2001) Effects of cyclopiazonic acid on cytosolic calcium in bovine airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 281:L126-33
Madison, J M; Ethier, M F (2001) Interleukin-4 rapidly inhibits calcium transients in response to carbachol in bovine airway smooth muscle cells. Am J Respir Cell Mol Biol 25:239-44
Ethier, M F; Dextradeur, T; Schaefer, O P et al. (2000) Effects of salmeterol on muscarinic inhibition of adenylyl cyclase in bovine trachealis cells. Life Sci 67:2753-8
Madison, J M; Ethier, M F; Yamaguchi, H (1998) Refilling of caffeine-sensitive intracellular calcium stores in bovine airway smooth muscle cells. Am J Physiol 275:L852-60

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