Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL054184-01A1
Application #
2232468
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1996-02-01
Project End
2001-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Rubin, Camelia Iancu; French, Deborah L; Atweh, George F (2003) Stathmin expression and megakaryocyte differentiation: a potential role in polyploidy. Exp Hematol 31:389-97
Mistry, S J; Benham, C J; Atweh, G F (2001) Development of ribozymes that target stathmin, a major regulator of the mitotic spindle. Antisense Nucleic Acid Drug Dev 11:41-9
Mistry, S J; Atweh, G F (2001) Stathmin inhibition enhances okadaic acid-induced mitotic arrest: a potential role for stathmin in mitotic exit. J Biol Chem 276:31209-15
Iancu, C; Mistry, S J; Arkin, S et al. (2001) Effects of stathmin inhibition on the mitotic spindle. J Cell Sci 114:909-16
Iancu, C; Mistry, S J; Arkin, S et al. (2000) Taxol and anti-stathmin therapy: a synergistic combination that targets the mitotic spindle. Cancer Res 60:3537-41
Lung, H Y; Meeus, I S; Weinberg, R S et al. (2000) In vivo silencing of the human gamma-globin gene in murine erythroid cells following retroviral transduction. Blood Cells Mol Dis 26:613-9
Atweh, G F; Sutton, M; Nassif, I et al. (1999) Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease. Blood 93:1790-7
Mistry, S J; Atweh, G F (1999) Stathmin expression in immortalized and oncogene transformed cells. Anticancer Res 19:573-7
Hosono, S; Luo, X; Hyink, D P et al. (1999) WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts. Oncogene 18:417-27