Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL054187-01A2
Application #
2232474
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1996-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Merchak, Assaad; Janssen, Daphne J; Bohlin, Kajsa et al. (2002) Endogenous pulmonary surfactant metabolism is not affected by mode of ventilation in premature infants with respiratory distress syndrome. J Pediatr 140:693-8
Nogee, L M; Dunbar 3rd, A E; Wert, S E et al. (2001) A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N Engl J Med 344:573-9
Amin, R S; Wert, S E; Baughman, R P et al. (2001) Surfactant protein deficiency in familial interstitial lung disease. J Pediatr 139:85-92
King, E L; Shackelford, G D; Hamvas, A (2001) High-frequency oscillation and paralysis stabilize surfactant protein-B--deficient infants. J Perinatol 21:421-5
Cole, F S; Hamvas, A; Nogee, L M (2001) Genetic disorders of neonatal respiratory function. Pediatr Res 50:157-62
Hamvas, A; Trusgnich, M; Brice, H et al. (2001) Population-based screening for rare mutations: high-throughput DNA extraction and molecular amplification from Guthrie cards. Pediatr Res 50:666-8
Nogee, L M; Wert, S E; Proffit, S A et al. (2000) Allelic heterogeneity in hereditary surfactant protein B (SP-B) deficiency. Am J Respir Crit Care Med 161:973-81
Cole, F S; Hamvas, A; Rubinstein, P et al. (2000) Population-based estimates of surfactant protein B deficiency. Pediatrics 105:538-41
Tryka, A F; Wert, S E; Mazursky, J E et al. (2000) Absence of lamellar bodies with accumulation of dense bodies characterizes a novel form of congenital surfactant defect. Pediatr Dev Pathol 3:335-45
Hamvas, A (2000) Disparate outcomes for very low birth weight infants: genetics, environment, or both? J Pediatr 136:427-8

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