Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL054188-02
Application #
2232476
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1995-05-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Lader, Alan S; Lee, Justin J; Cicchetti, Gregor et al. (2005) Mechanisms of gelsolin-dependent and -independent EGF-stimulated cell motility in a human lung epithelial cell line. Exp Cell Res 307:153-63
Lader, Alan S; Ramoni, Marco F; Zetter, Bruce R et al. (2004) Identification of a transcriptional profile associated with in vitro invasion in non-small cell lung cancer cell lines. Cancer Biol Ther 3:624-31
Harms, Christoph; Bosel, Julian; Lautenschlager, Marion et al. (2004) Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization. Mol Cell Neurosci 25:69-82
Glogauer, Michael; Marchal, Christophe C; Zhu, Fei et al. (2003) Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions. J Immunol 170:5652-7
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Azuma, T; Koths, K; Flanagan, L et al. (2000) Gelsolin in complex with phosphatidylinositol 4,5-bisphosphate inhibits caspase-3 and -9 to retard apoptotic progression. J Biol Chem 275:3761-6
Crowley, M R; Head, K L; Kwiatkowski, D J et al. (2000) The mouse mammary gland requires the actin-binding protein gelsolin for proper ductal morphogenesis. Dev Biol 225:407-23
Lueck, A; Yin, H L; Kwiatkowski, D J et al. (2000) Calcium regulation of gelsolin and adseverin: a natural test of the helix latch hypothesis. Biochemistry 39:5274-9

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