Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL055377-01A1
Application #
2233947
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Hassoun, Paul M; Filippov, Galina; Fogel, Michael et al. (2004) Hypoxia decreases expression of soluble guanylate cyclase in cultured rat pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol 30:908-13
Raveh, Yehuda; Ichinose, Fumito; Orbach, Pini et al. (2002) Radical scavengers protect murine lungs from endotoxin-induced hyporesponsiveness to inhaled nitric oxide. Anesthesiology 96:926-33
Schmidt, U; Han, R O; DiSalvo, T G et al. (2001) Cessation of platelet-mediated cyclic canine coronary occlusion after thrombolysis by combining nitric oxide inhalation with phosphodiesterase-5 inhibition. J Am Coll Cardiol 37:1981-8
Takata, M; Filippov, G; Liu, H et al. (2001) Cytokines decrease sGC in pulmonary artery smooth muscle cells via NO-dependent and NO-independent mechanisms. Am J Physiol Lung Cell Mol Physiol 280:L272-8
Holzmann, A; Manktelow, C; Weimann, J et al. (2001) Inhibition of lung phosphodiesterase improves responsiveness to inhaled nitric oxide in isolated-perfused lungs from rats challenged with endotoxin. Intensive Care Med 27:251-7
Ichinose, F; Zapol, W M; Sapirstein, A et al. (2001) Attenuation of hypoxic pulmonary vasoconstriction by endotoxemia requires 5-lipoxygenase in mice. Circ Res 88:832-8
Roberts Jr, J D; Chiche, J D; Weimann, J et al. (2000) Nitric oxide inhalation decreases pulmonary artery remodeling in the injured lungs of rat pups. Circ Res 87:140-5
Weimann, J; Ullrich, R; Hromi, J et al. (2000) Sildenafil is a pulmonary vasodilator in awake lambs with acute pulmonary hypertension. Anesthesiology 92:1702-12
Bloch, D B; Nakajima, A; Gulick, T et al. (2000) Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator. Mol Cell Biol 20:6138-46
Ullrich, R; Scherrer-Crosbie, M; Bloch, K D et al. (2000) Congenital deficiency of nitric oxide synthase 2 protects against endotoxin-induced myocardial dysfunction in mice. Circulation 102:1440-6

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