APOA-I Primary Sequence in HDL Assembly and Function - Trudy Forte

Abstract

Funding Agency

Agency: National Institute of Health (NIH)
Institute: National Heart, Lung, and Blood Institute (NHLBI)
Type: Research Project (R01)
Project #: 2R01HL055493-04
Application #: 6330892
Study Section: Special Emphasis Panel (ZRG1-SSS-T (01))
Program Officer: Applebaum-Bowden, Deborah

Project Start: 1997-08-01
Project End: 2003-03-31
Budget Start: 2001-04-01
Budget End: 2002-03-31
Support Year: 4
Fiscal Year: 2001
Total Cost: $356,025
Indirect Cost

Institution

Name: Lawrence Berkeley National Laboratory
Department
Type: Organized Research Units
DUNS #: 078576738

City: Berkeley
State: CA
Country: United States
Zip Code: 94720

Related projects


NIH 2002 R01 HL	APOA-I Primary Sequence in HDL Assembly and Function Forte, Trudy M. / Lawrence Berkeley National Laboratory	$356,025
NIH 2001 R01 HL	APOA-I Primary Sequence in HDL Assembly and Function Forte, Trudy M. / Lawrence Berkeley National Laboratory	$356,025
NIH 1999 R01 HL	Apoa-I Primary Sequence in Hdl Assembly and Function Forte, Trudy M. / Lawrence Berkeley National Laboratory
NIH 1998 R01 HL	Apoa-I Primary Sequence in Hdl Assembly and Function Forte, Trudy M. / Lawrence Berkeley National Laboratory
NIH 1997 R01 HL	Apoa-I Primary Sequence in Hdl Assembly and Function Forte, Trudy M. / Lawrence Berkeley National Laboratory

Publications

Parolini, Cinzia; Chiesa, Giulia; Gong, Elaine et al. (2005) Apolipoprotein A-I and the molecular variant apoA-I(Milano): evaluation of the antiatherogenic effects in knock-in mouse model. Atherosclerosis 183:222-9

Natarajan, Pradeep; Forte, Trudy M; Chu, Berbie et al. (2004) Identification of an apolipoprotein A-I structural element that mediates cellular cholesterol efflux and stabilizes ATP binding cassette transporter A1. J Biol Chem 279:24044-52

Parolini, Cinzia; Chiesa, Giulia; Zhu, Yiwen et al. (2003) Targeted replacement of mouse apolipoprotein A-I with human ApoA-I or the mutant ApoA-IMilano. Evidence of APOA-IM impaired hepatic secretion. J Biol Chem 278:4740-6

Beckstead, Jennifer A; Oda, Michael N; Martin, Dale D O et al. (2003) Structure-function studies of human apolipoprotein A-V: a regulator of plasma lipid homeostasis. Biochemistry 42:9416-23

Jia, Zhen; Natarajan, Pradeep; Forte, Trudy M et al. (2002) Thiol-bearing synthetic peptides retain the antioxidant activity of apolipoproteinA-I(Milano). Biochem Biophys Res Commun 297:206-13

Bielicki, John K; Oda, Michael N (2002) Apolipoprotein A-I(Milano) and apolipoprotein A-I(Paris) exhibit an antioxidant activity distinct from that of wild-type apolipoprotein A-I. Biochemistry 41:2089-96

Oda, M N; Bielicki, J K; Berger, T et al. (2001) Cysteine substitutions in apolipoprotein A-I primary structure modulate paraoxonase activity. Biochemistry 40:1710-8

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