Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL055583-01A1
Application #
2234183
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Mahapatra, Nitish R; Mahata, Manjula; O'Connor, Daniel T et al. (2003) Secretin activation of chromogranin A gene transcription. Identification of the signaling pathways in cis and in trans. J Biol Chem 278:19986-94
Mahata, Manjula; Mahapatra, Nitish R; O'Connor, Daniel T et al. (2002) Chromaffin cell catecholamine secretion: bisindolylmaleimide compounds exhibit novel and potent antagonist effects at the nicotinic cholinergic receptor in pheochromocytoma cells. Mol Pharmacol 61:1340-7
Mahata, S K; Mahata, M; Wakade, A R et al. (2000) Primary structure and function of the catecholamine release inhibitory peptide catestatin (chromogranin A(344-364)): identification of amino acid residues crucial for activity. Mol Endocrinol 14:1525-35
Mahapatra, N R; Mahata, M; Datta, A K et al. (2000) Neuroendocrine cell type-specific and inducible expression of the chromogranin B gene: crucial role of the proximal promoter. Endocrinology 141:3668-78
Mahata, S K; Mahata, M; Livsey Taylor, C V et al. (2000) The novel catecholamine release-inhibitory peptide catestatin (chromogranin A344-364). Properties and function. Adv Exp Med Biol 482:263-77
Mahata, S K; Mahata, M; Livsey, C V et al. (1999) Neuroendocrine cell type-specific and inducible expression of the secretogranin II gene: crucial role of cyclic adenosine monophosphate and serum response elements. Endocrinology 140:739-49
Mahata, S K; Mahata, M; Parmer, R J et al. (1999) Desensitization of catecholamine release. The novel catecholamine release-inhibitory peptide catestatin (chromogranin a344-364) acts at the receptor to prevent nicotinic cholinergic tolerance. J Biol Chem 274:2920-8
Mahata, S K; Mahata, M; Wu, H et al. (1999) Neurotrophin activation of catecholamine storage vesicle protein gene expression: signaling to chromogranin a biosynthesis. Neuroscience 88:405-24
Kennedy, B P; Mahata, S K; O'Connor, D T et al. (1998) Mechanism of cardiovascular actions of the chromogranin A fragment catestatin in vivo. Peptides 19:1241-8
Mahata, M; Mahata, S K; Parmer, R J et al. (1998) Proadrenomedullin N-terminal 20 peptide: minimal active region to regulate nicotinic receptors. Hypertension 32:907-16