Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL055620-01A1
Application #
2029703
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1996-09-15
Project End
1997-08-31
Budget Start
1996-09-15
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
Seta, Francesca; Cohen, Richard A (2014) The endothelium: paracrine mediator of aortic dissection. Circulation 129:2629-32
Bayat, Hossein; Xu, Shanqin; Pimentel, David et al. (2008) Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling. Arterioscler Thromb Vasc Biol 28:127-34
Ying, Jia; Clavreul, Nicolas; Sethuraman, Mahadevan et al. (2007) Thiol oxidation in signaling and response to stress: detection and quantification of physiological and pathophysiological thiol modifications. Free Radic Biol Med 43:1099-108
Xu, Shanqin; Ying, Jia; Jiang, Bingbing et al. (2006) Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging. Am J Physiol Heart Circ Physiol 290:H2220-7
Pimentel, David R; Adachi, Takeshi; Ido, Yasuo et al. (2006) Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation. J Mol Cell Cardiol 41:613-22
Clavreul, Nicolas; Bachschmid, Markus M; Hou, Xiuyun et al. (2006) S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein. Arterioscler Thromb Vasc Biol 26:2454-61
Xu, Shanqin; Bayat, Hossein; Hou, Xiuyun et al. (2006) Ribosomal S6 kinase-1 modulates interleukin-1beta-induced persistent activation of NF-kappaB through phosphorylation of IkappaBbeta. Am J Physiol Cell Physiol 291:C1336-45
Matsui, Reiko; Xu, Shanqin; Maitland, Karlene A et al. (2006) Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice. Arterioscler Thromb Vasc Biol 26:910-6
Matsui, Reiko; Xu, Shanqin; Maitland, Karlene A et al. (2005) Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II. Circulation 112:257-63
Adachi, Takeshi; Pimentel, David R; Heibeck, Tyler et al. (2004) S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells. J Biol Chem 279:29857-62

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