Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL055718-02
Application #
2234350
Study Section
Special Emphasis Panel (ZHL1-CSR-Q (S2))
Project Start
1995-09-30
Project End
2000-04-30
Budget Start
1996-07-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Christmas, Peter; Carlesso, Nadia; Shang, Haibo et al. (2003) Myeloid expression of cytochrome P450 4F3 is determined by a lineage-specific alternative promoter. J Biol Chem 278:25133-42
Cheng, T; Shen, H; Rodrigues, N et al. (2001) Transforming growth factor beta 1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21(Cip1/Waf1) or p27(Kip1). Blood 98:3643-9
Shen, H; Cheng, T; Olszak, I et al. (2001) CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells. J Immunol 166:5027-33
Christmas, P; Jones, J P; Patten, C J et al. (2001) Alternative splicing determines the function of CYP4F3 by switching substrate specificity. J Biol Chem 276:38166-72
Eppich, H M; Foxall, R; Gaynor, K et al. (2000) Pulsed electric fields for selection of hematopoietic cells and depletion of tumor cell contaminants. Nat Biotechnol 18:882-7
Cheng, T; Rodrigues, N; Dombkowski, D et al. (2000) Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat Med 6:1235-40
Shen, H; Cheng, T; Preffer, F I et al. (1999) Intrinsic human immunodeficiency virus type 1 resistance of hematopoietic stem cells despite coreceptor expression. J Virol 73:728-37
Carlesso, N; Aster, J C; Sklar, J et al. (1999) Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 93:838-48
Gardner, J P; Rosenzweig, M; Marks, D F et al. (1998) T-lymphopoietic capacity of cord blood-derived CD34+ progenitor cells. Exp Hematol 26:991-9
Gardner, J P; Zhu, H; Colosi, P C et al. (1997) Robust, but transient expression of adeno-associated virus-transduced genes during human T lymphopoiesis. Blood 90:4854-64