Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL056035-01
Application #
2234654
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1996-03-01
Project End
2001-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Biomedical Research Institute
Department
Type
DUNS #
058893371
City
Watertown
State
MA
Country
United States
Zip Code
02472
D'Angelo, Gerard; Adam, Leonard P (2002) Inhibition of ERK attenuates force development by lowering myosin light chain phosphorylation. Am J Physiol Heart Circ Physiol 282:H602-10
Kim, I; Je, H D; Gallant, C et al. (2000) Ca2+-calmodulin-dependent protein kinase II-dependent activation of contractility in ferret aorta. J Physiol 526 Pt 2:367-74
D'Angelo, G; Graceffa, P; Wang, C A et al. (1999) Mammal-specific, ERK-dependent, caldesmon phosphorylation in smooth muscle. Quantitation using novel anti-phosphopeptide antibodies. J Biol Chem 274:30115-21
Menice, C B; Hulvershorn, J; Adam, L P et al. (1997) Calponin and mitogen-activated protein kinase signaling in differentiated vascular smooth muscle. J Biol Chem 272:25157-61
Pyles, J M; March, K L; Franklin, M et al. (1997) Activation of MAP kinase in vivo follows balloon overstretch injury of porcine coronary and carotid arteries. Circ Res 81:904-10
Franklin, M T; Wang, C L; Adam, L P (1997) Stretch-dependent activation and desensitization of mitogen-activated protein kinase in carotid arteries. Am J Physiol 273:C1819-27
Graceffa, P; Adam, L P; Morgan, K G (1996) Strong interaction between caldesmon and calponin. J Biol Chem 271:30336-9
Mohler, E R; Franklin, M T; Adam, L P (1996) Intracellular signaling by 8-epi-prostaglandin F2 alpha is mediated by thromboxane A2/prostaglandin endoperoxide receptors in porcine carotid arteries. Biochem Biophys Res Commun 225:915-23