Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL056370-01
Application #
2234926
Study Section
Special Emphasis Panel (ZRG4-CVB (03))
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Singh, Sonia R; Robbins, Jeffrey (2018) Desmin and Cardiac Disease: An Unfolding Story. Circ Res 122:1324-1326
Lowey, Susan; Bretton, Vera; Joel, Peteranne B et al. (2018) Hypertrophic cardiomyopathy R403Q mutation in rabbit ?-myosin reduces contractile function at the molecular and myofibrillar levels. Proc Natl Acad Sci U S A 115:11238-11243
Waggoner, Jason R; Ginsburg, Kenneth S; Mitton, Bryan et al. (2009) Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport. Am J Physiol Heart Circ Physiol 296:H698-703
Sadayappan, Sakthivel; Finley, Natosha; Howarth, Jack W et al. (2008) Role of the acidic N'region of cardiac troponin I in regulating myocardial function. FASEB J 22:1246-57
Pattison, James Scott; Waggoner, Jason R; James, Jeanne et al. (2008) Phospholamban overexpression in transgenic rabbits. Transgenic Res 17:157-70
Sadayappan, Sakthivel; Robbins, Jeffrey (2008) The death of transcriptional chauvinism in the control and regulation of cardiac contractility. Ann N Y Acad Sci 1123:1-9
Nakamura, Tomoki; Colbert, Melissa; Krenz, Maike et al. (2007) Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome. J Clin Invest 117:2123-32
Krenz, Maike; Sadayappan, Sakthivel; Osinska, Hanna E et al. (2007) Distribution and structure-function relationship of myosin heavy chain isoforms in the adult mouse heart. J Biol Chem 282:24057-64
Maloyan, Alina; Gulick, James; Glabe, Charles G et al. (2007) Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy. Proc Natl Acad Sci U S A 104:5995-6000
Yutzey, Katherine E; Robbins, Jeffrey (2007) Principles of genetic murine models for cardiac disease. Circulation 115:792-9

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