Rage and Vascular Disease in Diabetes

Stern, David M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 1R01HL056881-01
• Application #: 2235307
• Study Section: Special Emphasis Panel (ZRG4-CVB (01))
• Project Start: 1996-07-01
• Project End: 2001-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Columbia University (N.Y.)
• Department: Physiology
• Type: Schools of Medicine
• DUNS #: 167204994
• City: New York
• State: NY
• Country: United States
• Zip Code: 10032

Publications

Lue, L F; Walker, D G; Brachova, L et al. (2001) Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Exp Neurol 171:29-45

Hofmann, M A; Drury, S; Fu, C et al. (1999) RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97:889-901

Kislinger, T; Fu, C; Huber, B et al. (1999) N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J Biol Chem 274:31740-9

Park, L; Raman, K G; Lee, K J et al. (1998) Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat Med 4:1025-31