Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL058248-01
Application #
2031450
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
1996-09-30
Project End
2001-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Type
Organized Research Units
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Remington, Nicole; Stevens, Robert D; Wells, Randall S et al. (2007) Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins. Gene 398:123-31
Bonaventura, Celia; Fago, Angela; Henkens, Robert et al. (2004) Critical redox and allosteric aspects of nitric oxide interactions with hemoglobin. Antioxid Redox Signal 6:979-91
Bonaventura, C; Crumbliss, A L; Weber, R E (2004) New insights into the proton-dependent oxygen affinity of Root effect haemoglobins. Acta Physiol Scand 182:245-58
Tsai, Ching-Hsuan; Simplaceanu, Virgil; Ho, Nancy T et al. (2003) Site mutations disrupt inter-helical H-bonds (alpha14W-alpha67T and beta15W-beta72S) involved in kinetic steps in the hemoglobin R-->T transition without altering the free energies of oxygenation. Biophys Chem 100:131-42
Fago, Angela; Crumbliss, Alvin L; Peterson, Jim et al. (2003) The case of the missing NO-hemoglobin: spectral changes suggestive of heme redox reactions reflect changes in NO-heme geometry. Proc Natl Acad Sci U S A 100:12087-92
Bonaventura, Celia; Taboy, Celine H; Low, Philip S et al. (2002) Heme redox properties of S-nitrosated hemoglobin A0 and hemoglobin S: implications for interactions of nitric oxide with normal and sickle red blood cells. J Biol Chem 277:14557-63
Taboy, Celine H; Bonaventura, Celia; Crumbliss, Alvin L (2002) Anaerobic oxidations of myoglobin and hemoglobin by spectroelectrochemistry. Methods Enzymol 353:187-209
Dantsker, David; Samuni, Uri; Friedman, Adam J et al. (2002) Geminate rebinding in trehalose-glass embedded myoglobins reveals residue-specific control of intramolecular trajectories. J Mol Biol 315:239-51
Juszczak, Laura J; Manjula, Belur; Bonaventura, Celia et al. (2002) UV resonance Raman study of beta93-modified hemoglobin A: chemical modifier-specific effects and added influences of attached poly(ethylene glycol) chains. Biochemistry 41:376-85
Bonaventura, Celia; Godette, Gerald; Ferruzzi, Giulia et al. (2002) Responses of normal and sickle cell hemoglobin to S-nitroscysteine: implications for therapeutic applications of NO in treatment of sickle cell disease. Biophys Chem 98:165-81

Showing the most recent 10 out of 17 publications