Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL058398-02
Application #
2861168
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1997-09-01
Project End
2001-08-31
Budget Start
1998-09-01
Budget End
1999-08-31
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Pier, Gerald B (2012) The challenges and promises of new therapies for cystic fibrosis. J Exp Med 209:1235-9
Campodonico, Victoria L; Llosa, Nicolas J; Grout, Martha et al. (2010) Evaluation of flagella and flagellin of Pseudomonas aeruginosa as vaccines. Infect Immun 78:746-55
Gadjeva, Mihaela; Paradis-Bleau, Catherine; Priebe, Gregory P et al. (2010) Caveolin-1 modifies the immunity to Pseudomonas aeruginosa. J Immunol 184:296-302
Ulrich, Martina; Worlitzsch, Dieter; Viglio, Simona et al. (2010) Alveolar inflammation in cystic fibrosis. J Cyst Fibros 9:217-27
Bajmoczi, Milan; Gadjeva, Mihaela; Alper, Seth L et al. (2009) Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa. Am J Physiol Cell Physiol 297:C263-77
Levy, Hara; Murphy, Amy; Zou, Fei et al. (2009) IL1B polymorphisms modulate cystic fibrosis lung disease. Pediatr Pulmonol 44:580-93
Kowalski, Michael P; Dubouix-Bourandy, Anne; Bajmoczi, Milan et al. (2007) Host resistance to lung infection mediated by major vault protein in epithelial cells. Science 317:130-2
Reiniger, Nina; Ichikawa, Jeffrey K; Pier, Gerald B (2005) Influence of cystic fibrosis transmembrane conductance regulator on gene expression in response to Pseudomonas aeruginosa infection of human bronchial epithelial cells. Infect Immun 73:6822-30
Kowalski, Michael P; Pier, Gerald B (2004) Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. J Immunol 172:418-25
Cannon, Carolyn L; Kowalski, Michael P; Stopak, Kimberly S et al. (2003) Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol 29:188-97

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