Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL059428-01
Application #
2453328
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1997-12-22
Project End
1998-08-31
Budget Start
1997-12-22
Budget End
1998-08-31
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Brown, R Dale; Ambler, S Kelly; Li, Min et al. (2013) MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension. Am J Physiol Heart Circ Physiol 304:H269-81
Jeong, Mark Y; Walker, John S; Brown, R Dale et al. (2010) AFos inhibits phenylephrine-mediated contractile dysfunction by altering phospholamban phosphorylation. Am J Physiol Heart Circ Physiol 298:H1719-26
Miyamoto, Shelley D; Brown, R D; Robinson, Bridget A et al. (2009) Cardiac cell-specific apoptotic and cytokine responses to reovirus infection: determinants of myocarditic phenotype. J Card Fail 15:529-39
Mitchell, M Darren; Laird, Rebecca E; Brown, R Dale et al. (2007) IL-1beta stimulates rat cardiac fibroblast migration via MAP kinase pathways. Am J Physiol Heart Circ Physiol 292:H1139-47
Brown, R Dale; Ambler, S Kelly; Mitchell, M Darren et al. (2005) The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 45:657-87
Long, C S (2001) The role of interleukin-1 in the failing heart. Heart Fail Rev 6:81-94
Koudssi, F; Lopez, J E; Villegas, S et al. (1998) Cardiac fibroblasts arrest at the G1/S restriction point in response to interleukin (IL)-1beta. Evidence for IL-1beta-induced hypophosphorylation of the retinoblastoma protein. J Biol Chem 273:25796-803