Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL061364-05
Application #
6612604
Study Section
Special Emphasis Panel (ZRG1-PTHA (01))
Program Officer
Srinivas, Pothur R
Project Start
1999-07-06
Project End
2004-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
5
Fiscal Year
2003
Total Cost
$428,801
Indirect Cost
Name
University of Pennsylvania
Department
Pharmacology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Ky, Bonnie; Burke, Anne; Tsimikas, Sotirios et al. (2008) The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans. J Am Coll Cardiol 51:1653-62
Rokach, Joshua; Kim, Seongjin; Bellone, Sophie et al. (2004) Total synthesis of isoprostanes: discovery and quantitation in biological systems. Chem Phys Lipids 128:35-56
Pratico, Domenico; Rokach, Joshua; Lawson, John et al. (2004) F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases. Chem Phys Lipids 128:165-71
Ide, Tomomi; Egan, Karine; Bell-Parikh, L Chastine et al. (2003) Activation of nuclear receptors by prostaglandins. Thromb Res 110:311-5
Burke, Anne; Fitzgerald, Garret A (2003) Oxidative stress and smoking-induced vascular injury. Prog Cardiovasc Dis 46:79-90
Zhang, Zhibing; Vezza, Roberta; Plappert, Theodore et al. (2003) COX-2-dependent cardiac failure in Gh/tTG transgenic mice. Circ Res 92:1153-61
Bell-Parikh, L Chastine; Ide, Tomomi; Lawson, John A et al. (2003) Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma. J Clin Invest 112:945-55
Burke, Anne; FitzGerald, Garret A; Lucey, Michael R (2002) A prospective analysis of oxidative stress and liver transplantation. Transplantation 74:217-21
Cyrus, Tillmann; Sung, Syuan; Zhao, Lei et al. (2002) Effect of low-dose aspirin on vascular inflammation, plaque stability, and atherogenesis in low-density lipoprotein receptor-deficient mice. Circulation 106:1282-7
Cyrus, T; Pratico, D; Zhao, L et al. (2001) Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice. Circulation 103:2277-82

Showing the most recent 10 out of 21 publications