Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL061407-06
Application #
6702296
Study Section
Lung Biology and Pathology Study Section (LBPA)
Program Officer
Harabin, Andrea L
Project Start
1998-12-07
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
6
Fiscal Year
2004
Total Cost
$341,100
Indirect Cost

  Institution

Name
National Jewish Health
Department
Type
DUNS #
076443019
City
Denver
State
CO
Country
United States
Zip Code
80206

  Publications

Zemans, Rachel L; Briones, Natalie; Young, Scott K et al. (2009) A novel method for long term bone marrow culture and genetic modification of murine neutrophils via retroviral transduction. J Immunol Methods 340:102-15
Smoak, Kathleen; Madenspacher, Jennifer; Jeyaseelan, Samithamby et al. (2008) Effects of liver X receptor agonist treatment on pulmonary inflammation and host defense. J Immunol 180:3305-12
Fessler, Michael B; Arndt, Patrick G; Just, Ingo et al. (2007) Dual role for RhoA in suppression and induction of cytokines in the human neutrophil. Blood 109:1248-56
Arndt, Patrick G; Young, Scott K; Poch, Katie R et al. (2006) Systemic inhibition of the angiotensin-converting enzyme limits lipopolysaccharide-induced lung neutrophil recruitment through both bradykinin and angiotensin II-regulated pathways. J Immunol 177:7233-41
Walker, Travis S; Tomlin, Kerry L; Worthen, G Scott et al. (2005) Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect Immun 73:3693-701
Arndt, Patrick G; Young, Scott K; Lieber, Jonathan G et al. (2005) Inhibition of c-Jun N-terminal kinase limits lipopolysaccharide-induced pulmonary neutrophil influx. Am J Respir Crit Care Med 171:978-86
Fessler, Michael B; Young, Scott K; Jeyaseelan, Samithamby et al. (2005) A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense. Am J Respir Crit Care Med 171:606-15
Fessler, Michael B; Arndt, Patrick G; Frasch, S Courtney et al. (2004) Lipid rafts regulate lipopolysaccharide-induced activation of Cdc42 and inflammatory functions of the human neutrophil. J Biol Chem 279:39989-98
Malcolm, Kenneth C; Worthen, G Scott (2003) Lipopolysaccharide stimulates p38-dependent induction of antiviral genes in neutrophils independently of paracrine factors. J Biol Chem 278:15693-701
Avdi, Natalie J; Malcolm, Kenneth C; Nick, Jerry A et al. (2002) A role for protein phosphatase-2A in p38 mitogen-activated protein kinase-mediated regulation of the c-Jun NH(2)-terminal kinase pathway in human neutrophils. J Biol Chem 277:40687-96

Showing the most recent 10 out of 11 publications