Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL063238-02
Application #
6390470
Study Section
Pharmacology A Study Section (PHRA)
Program Officer
Reinlib, Leslie
Project Start
2000-04-10
Project End
2004-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
2
Fiscal Year
2001
Total Cost
$216,000
Indirect Cost
Name
University of Toledo
Department
Physiology
Type
Schools of Medicine
DUNS #
807418939
City
Toledo
State
OH
Country
United States
Zip Code
43614
Kennedy, David J; Vetteth, Sandeep; Xie, Miaorong et al. (2006) Ouabain decreases sarco(endo)plasmic reticulum calcium ATPase activity in rat hearts by a process involving protein oxidation. Am J Physiol Heart Circ Physiol 291:H3003-11
Kennedy, David J; Vetteth, Sandeep; Periyasamy, Sankaridrug M et al. (2006) Central role for the cardiotonic steroid marinobufagenin in the pathogenesis of experimental uremic cardiomyopathy. Hypertension 47:488-95
Shapiro, J I; Kennedy, D J; Malhotra, D et al. (2006) Hypokalemia potentiates ouabain's effect on calcium cycling and cardiac growth. Cell Mol Biol (Noisy-le-grand) 52:87-91
Liu, Lijun; Li, Jie; Liu, Jiang et al. (2006) Involvement of Na+/K+-ATPase in hydrogen peroxide-induced hypertrophy in cardiac myocytes. Free Radic Biol Med 41:1548-56
Oweis, Shadi; Wu, Liang; Kiela, Pawel R et al. (2006) Cardiac glycoside downregulates NHE3 activity and expression in LLC-PK1 cells. Am J Physiol Renal Physiol 290:F997-1008
Kesiry, Riad; Liu, Jiang (2005) GRP78/BIP is involved in ouabain-induced endocytosis of the Na/K-ATPase in LLC-PK1 cells. Front Biosci 10:2045-55
Liu, Jiang; Liang, Man; Liu, Lijun et al. (2005) Ouabain-induced endocytosis of the plasmalemmal Na/K-ATPase in LLC-PK1 cells requires caveolin-1. Kidney Int 67:1844-54
Periyasamy, Sankaridrug M; Liu, Jiang; Tanta, Feras et al. (2005) Salt loading induces redistribution of the plasmalemmal Na/K-ATPase in proximal tubule cells. Kidney Int 67:1868-77
Xie, Zijian; Xie, Joe (2005) The Na/K-ATPase-mediated signal transduction as a target for new drug development. Front Biosci 10:3100-9
Liu, Jiang (2005) Ouabain-induced endocytosis and signal transduction of the Na/K-ATPase. Front Biosci 10:2056-63

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