Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL065192-05
Application #
6780437
Study Section
Special Emphasis Panel (ZHL1-CSR-B (M1))
Program Officer
Ganguly, Pankaj
Project Start
2000-08-15
Project End
2005-07-31
Budget Start
2004-08-01
Budget End
2005-07-31
Support Year
5
Fiscal Year
2004
Total Cost
$264,250
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Balagopal, P; George, D; Sweeten, S et al. (2008) Response of fractional synthesis rate (FSR) of fibrinogen, concentration of D-dimer and fibrinolytic balance to physical activity-based intervention in obese children. J Thromb Haemost 6:1296-303
Devin, Jessica K; Johnson, Joyce E; Eren, Mesut et al. (2007) Transgenic overexpression of plasminogen activator inhibitor-1 promotes the development of polycystic ovarian changes in female mice. J Mol Endocrinol 39:9-16
Schoenhard, John A; Muldowney 3rd, James A S; Emens, Jonathan S et al. (2007) Plasminogen activator inhibitor-1 has a circadian rhythm in blind individuals. Thromb Haemost 98:479-81
Eren, M; Gleaves, L A; Atkinson, J B et al. (2007) Reactive site-dependent phenotypic alterations in plasminogen activator inhibitor-1 transgenic mice. J Thromb Haemost 5:1500-8
De Taeye, Bart M; Novitskaya, Tatiana; McGuinness, Owen P et al. (2007) Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity. Am J Physiol Endocrinol Metab 293:E713-25
Muldowney 3rd, James A S; Painter, Corrie A; Sanders-Bush, Elaine et al. (2007) Acute tissue-type plasminogen activator release in human microvascular endothelial cells: the roles of Galphaq, PLC-beta, IP3 and 5,6-epoxyeicosatrienoic acid. Thromb Haemost 97:263-71
Muldowney 3rd, James A S; Stringham, John R; Levy, Shawn E et al. (2007) Antiproliferative agents alter vascular plasminogen activator inhibitor-1 expression: a potential prothrombotic mechanism of drug-eluting stents. Arterioscler Thromb Vasc Biol 27:400-6
Fujita, Hideo; Kang, Myengmo; Eren, Mesut et al. (2006) Foxc2 is a common mediator of insulin and transforming growth factor beta signaling to regulate plasminogen activator inhibitor type I gene expression. Circ Res 98:626-34
De Taeye, Bart M; Novitskaya, Tatiana; Gleaves, Linda et al. (2006) Bone marrow plasminogen activator inhibitor-1 influences the development of obesity. J Biol Chem 281:32796-805
Smith, Layton H; Dixon, John D; Stringham, John R et al. (2006) Pivotal role of PAI-1 in a murine model of hepatic vein thrombosis. Blood 107:132-4

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