Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL067969-02
Application #
6688239
Study Section
Pathology A Study Section (PTHA)
Program Officer
Skarlatos, Sonia
Project Start
2002-12-05
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$303,000
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Tao, Zhengxian; Chen, Bo; Tan, Xiao et al. (2011) Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart. Proc Natl Acad Sci U S A 108:2064-9
Pons, Jennifer; Huang, Yu; Takagawa, Junya et al. (2009) Combining angiogenic gene and stem cell therapies for myocardial infarction. J Gene Med 11:743-53
Su, Hua; Takagawa, Junya; Huang, Yu et al. (2009) Additive effect of AAV-mediated angiopoietin-1 and VEGF expression on the therapy of infarcted heart. Int J Cardiol 133:191-7
Pons, Jennifer; Huang, Yu; Arakawa-Hoyt, Janice et al. (2008) VEGF improves survival of mesenchymal stem cells in infarcted hearts. Biochem Biophys Res Commun 376:419-22
Su, H; Yeghiazarians, Y; Lee, A et al. (2008) AAV serotype 1 mediates more efficient gene transfer to pig myocardium than AAV serotype 2 and plasmid. J Gene Med 10:33-41
Su, Hua; Kan, Yuet Wai (2007) Adeno-associated viral vector-delivered hypoxia-inducible gene expression in ischemic hearts. Methods Mol Biol 366:331-42
Su, H; Huang, Y; Takagawa, J et al. (2006) AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect. Gene Ther 13:1495-502
Su, Hua; Joho, Shuji; Huang, Yu et al. (2004) Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts. Proc Natl Acad Sci U S A 101:16280-5